Cylinder misfire (ignition or fuel)
Very commonOne cylinder is not producing its share of power — a fouled spark plug, a failed ignition coil, a cracked coil boot, a clogged injector or a stuck open injector. The engine shakes because it is now firing three or five or seven times per revolution instead of four or six or eight, and the missing pulse is a hole in the rotation.
How to spot it
A P0300 random misfire or a cylinder-specific code (P0301–P0308). A flashing check-engine light means an active misfire severe enough to damage the catalyst.
The fix
Diagnose the affected cylinder from the code, then replace the plug, coil or injector as indicated. If a coil moved to a good cylinder makes the misfire follow, the coil is at fault.